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Changes in duration of action of rocuronium following decrease in hepatic blood flow during pneumoperitoneum for laparoscopic gynaecological surgery

BACKGROUND: A moderate insufflation pressure and deep neuromuscular blockade (NMB) have been recommended in laparoscopic surgery in consideration of the possible reduction in splanchnic perfusion due to the CO(2)-pneumoperitoneum. Since the liver is the major organ for rocuronium metabolism, the que...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Cao, Wen, Liu, Yu, Wang, Yun, Lang, Ren, Yue, Yun, Wu, An-Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359965/
https://www.ncbi.nlm.nih.gov/pubmed/28320323
http://dx.doi.org/10.1186/s12871-017-0335-1