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Well-positioned nucleosomes punctuate polycistronic pol II transcription units and flank silent VSG gene arrays in Trypanosoma brucei

BACKGROUND: The compaction of DNA in chromatin in eukaryotes allowed the expansion of genome size and coincided with significant evolutionary diversification. However, chromatin generally represses DNA function, and mechanisms coevolved to regulate chromatin structure and its impact on DNA. This inc...

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Detalles Bibliográficos
Autores principales: Maree, Johannes Petrus, Povelones, Megan Lindsay, Clark, David Johannes, Rudenko, Gloria, Patterton, Hugh-George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359979/
https://www.ncbi.nlm.nih.gov/pubmed/28344657
http://dx.doi.org/10.1186/s13072-017-0121-9