Structural Insight into Anaphase Promoting Complex 3 Structure and Docking with a Natural Inhibitory Compound

BACKGROUND: Anaphase promoting complex (APC) is the biggest Cullin-RING E3 ligase and is very important in cell cycle control; many anti-cancer agents target this. APC controls the onset of chromosome separation and mitotic exit through securin and cyclin B degradation, respectively. Its APC3 subuni...

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Detalles Bibliográficos
Autores principales: Rahimi, Hamzeh, Shokrgozar, Mohammad Ali, Madadkar-Sobhani, Armin, Mahdian, Reza, Foroumadi, Alireza, Karimipoor, Morteza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359995/
https://www.ncbi.nlm.nih.gov/pubmed/28401073
http://dx.doi.org/10.4103/2277-9175.201683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359995/
https://www.ncbi.nlm.nih.gov/pubmed/28401073
http://dx.doi.org/10.4103/2277-9175.201683

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