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Regulatory T cell frequency, but not plasma IL-33 levels, represents potential immunological biomarker to predict clinical response to intravenous immunoglobulin therapy

BACKGROUND: Intravenous immunoglobulin (IVIG) is a polyspecific pooled immunoglobulin G preparation and one of the commonly used therapeutics for autoimmune diseases including those of neurological origin. A recent report in murine model proposed that IVIG expands regulatory T (T(reg)) cells via ind...

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Detalles Bibliográficos
Autores principales: Maddur, Mohan S., Stephen-Victor, Emmanuel, Das, Mrinmoy, Prakhar, Praveen, Sharma, Varun K., Singh, Vikas, Rabin, Magalie, Trinath, Jamma, Balaji, Kithiganahalli N., Bolgert, Francis, Vallat, Jean-Michel, Magy, Laurent, Kaveri, Srini V., Bayry, Jagadeesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360043/
https://www.ncbi.nlm.nih.gov/pubmed/28320438
http://dx.doi.org/10.1186/s12974-017-0818-5