Aflatoxin B(1) inhibits the type 1 interferon response pathway via STAT1 suggesting another mechanism of hepatocellular carcinoma

BACKGROUND: Aflatoxin B(1) (AFB(1)) contamination of food is very high in most sub-Saharan African countries. AFB(1) is known to cause hepatocellular carcinoma (HCC) by inducing mutation in the tumour suppressor gene TP53. The number of new HCC cases is high in West Africa with an accompanying high...

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Detalles Bibliográficos
Autores principales: Narkwa, Patrick W., Blackbourn, David J., Mutocheluh, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360051/
https://www.ncbi.nlm.nih.gov/pubmed/28344639
http://dx.doi.org/10.1186/s13027-017-0127-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360051/
https://www.ncbi.nlm.nih.gov/pubmed/28344639
http://dx.doi.org/10.1186/s13027-017-0127-8

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