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Aflatoxin B(1) inhibits the type 1 interferon response pathway via STAT1 suggesting another mechanism of hepatocellular carcinoma
BACKGROUND: Aflatoxin B(1) (AFB(1)) contamination of food is very high in most sub-Saharan African countries. AFB(1) is known to cause hepatocellular carcinoma (HCC) by inducing mutation in the tumour suppressor gene TP53. The number of new HCC cases is high in West Africa with an accompanying high...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360051/ https://www.ncbi.nlm.nih.gov/pubmed/28344639 http://dx.doi.org/10.1186/s13027-017-0127-8 |