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Palladium(0)-catalyzed asymmetric C(sp(3))–H arylation using a chiral binol-derived phosphate and an achiral ligand
The first efficient palladium(0)-catalyzed enantioselective C(sp(3))–H activation reaction using a catalytic chiral base and an achiral phosphine ligand is reported. Fine-tuning the binol-derived phosphoric acid pre-catalyst and the reaction conditions was found to be crucial to achieve high levels...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360168/ https://www.ncbi.nlm.nih.gov/pubmed/28451275 http://dx.doi.org/10.1039/c6sc04006c |