A metal-mediated base pair that discriminates between the canonical pyrimidine nucleobases

A nucleoside analogue comprising the ligand 1H-imidazo[4,5-f][1,10]phenanthroline (P) was applied to develop a molecular beacon capable of discriminating the canonical nucleobases cytosine and thymine. The beacon is based on the formation of a stable Ag(+)-mediated base pair between P and cytosine,...

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Detalles Bibliográficos
Autores principales: Jash, Biswarup, Scharf, Philipp, Sandmann, Nikolas, Fonseca Guerra, Célia, Megger, Dominik A., Müller, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360170/
https://www.ncbi.nlm.nih.gov/pubmed/28451274
http://dx.doi.org/10.1039/c6sc03482a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360170/
https://www.ncbi.nlm.nih.gov/pubmed/28451274
http://dx.doi.org/10.1039/c6sc03482a

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