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A metal-mediated base pair that discriminates between the canonical pyrimidine nucleobases
A nucleoside analogue comprising the ligand 1H-imidazo[4,5-f][1,10]phenanthroline (P) was applied to develop a molecular beacon capable of discriminating the canonical nucleobases cytosine and thymine. The beacon is based on the formation of a stable Ag(+)-mediated base pair between P and cytosine,...
Autores principales: | Jash, Biswarup, Scharf, Philipp, Sandmann, Nikolas, Fonseca Guerra, Célia, Megger, Dominik A., Müller, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360170/ https://www.ncbi.nlm.nih.gov/pubmed/28451274 http://dx.doi.org/10.1039/c6sc03482a |
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