Diacerein inhibits the pro-atherogenic & pro-inflammatory effects of IL-1 on human keratinocytes & endothelial cells

We investigated IL-1-induced regulation of genes related to inflammation and atherogenesis in human keratinocytes and endothelial cells, and if ‘diacerein’, an oral IL-1 inhibiting drug currently approved for use in osteoarthritis, would reverse IL-1’s effects on these cells. Primary human keratinoc...

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Detalles Bibliográficos
Autores principales: Mohan, Girish C., Zhang, Huayi, Bao, Lei, Many, Benjamin, Chan, Lawrence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360272/
https://www.ncbi.nlm.nih.gov/pubmed/28323859
http://dx.doi.org/10.1371/journal.pone.0173981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360272/
https://www.ncbi.nlm.nih.gov/pubmed/28323859
http://dx.doi.org/10.1371/journal.pone.0173981

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