A system for coordinated analysis of translational readthrough and nonsense-mediated mRNA decay

The nonsense-mediated mRNA decay (NMD) pathway degrades mRNAs containing premature termination codons, limiting the expression of potentially deleterious truncated proteins. This activity positions the pathway as a regulator of the severity of genetic diseases caused by nonsense mutations. Because m...

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Detalles Bibliográficos
Autores principales: Baker, Stacey L., Hogg, J. Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360307/
https://www.ncbi.nlm.nih.gov/pubmed/28323884
http://dx.doi.org/10.1371/journal.pone.0173980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360307/
https://www.ncbi.nlm.nih.gov/pubmed/28323884
http://dx.doi.org/10.1371/journal.pone.0173980

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