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miR-181b regulates vascular stiffness age dependently in part by regulating TGF-β signaling

BACKGROUND: Endothelial dysfunction and arterial stiffening play major roles in cardiovascular diseases. The critical role for the miR-181 family in vascular inflammation has been documented. Here we tested whether the miR-181 family can influence the pathogenesis of hypertension and vascular stiffe...

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Detalles Bibliográficos
Autores principales: Hori, Daijiro, Dunkerly-Eyring, Brittany, Nomura, Yohei, Biswas, Debjit, Steppan, Jochen, Henao-Mejia, Jorge, Adachi, Hideo, Santhanam, Lakshmi, Berkowitz, Dan E., Steenbergen, Charles, Flavell, Richard A., Das, Samarjit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360327/
https://www.ncbi.nlm.nih.gov/pubmed/28323879
http://dx.doi.org/10.1371/journal.pone.0174108