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miR-181b regulates vascular stiffness age dependently in part by regulating TGF-β signaling
BACKGROUND: Endothelial dysfunction and arterial stiffening play major roles in cardiovascular diseases. The critical role for the miR-181 family in vascular inflammation has been documented. Here we tested whether the miR-181 family can influence the pathogenesis of hypertension and vascular stiffe...
Autores principales: | Hori, Daijiro, Dunkerly-Eyring, Brittany, Nomura, Yohei, Biswas, Debjit, Steppan, Jochen, Henao-Mejia, Jorge, Adachi, Hideo, Santhanam, Lakshmi, Berkowitz, Dan E., Steenbergen, Charles, Flavell, Richard A., Das, Samarjit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360327/ https://www.ncbi.nlm.nih.gov/pubmed/28323879 http://dx.doi.org/10.1371/journal.pone.0174108 |
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