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GOST: A generic ordinal sequential trial design for a treatment trial in an emerging pandemic

BACKGROUND: Conducting clinical trials to assess experimental treatments for potentially pandemic infectious diseases is challenging. Since many outbreaks of infectious diseases last only six to eight weeks, there is a need for trial designs that can be implemented rapidly in the face of uncertainty...

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Detalles Bibliográficos
Autores principales: Whitehead, John, Horby, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360336/
https://www.ncbi.nlm.nih.gov/pubmed/28278301
http://dx.doi.org/10.1371/journal.pntd.0005439