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Inferring fitness landscapes and selection on phenotypic states from single-cell genealogical data

Recent advances in single-cell time-lapse microscopy have revealed non-genetic heterogeneity and temporal fluctuations of cellular phenotypes. While different phenotypic traits such as abundance of growth-related proteins in single cells may have differential effects on the reproductive success of c...

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Detalles Bibliográficos
Autores principales: Nozoe, Takashi, Kussell, Edo, Wakamoto, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360348/
https://www.ncbi.nlm.nih.gov/pubmed/28267748
http://dx.doi.org/10.1371/journal.pgen.1006653