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Inferring fitness landscapes and selection on phenotypic states from single-cell genealogical data
Recent advances in single-cell time-lapse microscopy have revealed non-genetic heterogeneity and temporal fluctuations of cellular phenotypes. While different phenotypic traits such as abundance of growth-related proteins in single cells may have differential effects on the reproductive success of c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360348/ https://www.ncbi.nlm.nih.gov/pubmed/28267748 http://dx.doi.org/10.1371/journal.pgen.1006653 |