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Albumin-based nanoparticles as methylprednisolone carriers for targeted delivery towards the neonatal Fc receptor in glomerular podocytes

Glucocorticoids (GCs) are commonly used in the treatment of nephrotic syndrome. However, high doses and long periods of GC therapy can result in severe side effects. The present study aimed to selectively deliver albumin-methylprednisolone (MP) nanoparticles towards glomerular podocytes, which highl...

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Detalles Bibliográficos
Autores principales: Wu, Lin, Chen, Mingyu, Mao, Huijuan, Wang, Ningning, Zhang, Bo, Zhao, Xiufen, Qian, Jun, Xing, Changying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360426/
https://www.ncbi.nlm.nih.gov/pubmed/28259932
http://dx.doi.org/10.3892/ijmm.2017.2902