AJS1669, a novel small-molecule muscle glycogen synthase activator, improves glucose metabolism and reduces body fat mass in mice

Impaired glycogen synthesis and turnover are common in insulin resistance and type 2 diabetes. As glycogen synthase (GS) is a key enzyme involved in the synthetic process, it presents a promising therapeutic target for the treatment of type 2 diabetes. In the present study, we identified a novel, po...

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Detalles Bibliográficos
Autores principales: Nakano, Kazuhiro, Takeshita, Sen, Kawasaki, Noriko, Miyanaga, Wataru, Okamatsu, Yoriko, Dohi, Mizuki, Nakagawa, Tadakiyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360432/
https://www.ncbi.nlm.nih.gov/pubmed/28290602
http://dx.doi.org/10.3892/ijmm.2017.2909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360432/
https://www.ncbi.nlm.nih.gov/pubmed/28290602
http://dx.doi.org/10.3892/ijmm.2017.2909

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