Cargando…

Epigenetic intervention with a BET inhibitor ameliorates acute retinal ganglion cell death in mice

PURPOSE: The bromo and extraterminal (BET) epigenetic “reader” family is becoming an appealing new therapeutic target for several common diseases, yet little is known of its role in retinal neurodegeneration. We explored the potential of BET inhibition in the protection of retinal ganglion cells (RG...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jun, Zhao, Lei, Urabe, Go, Fu, Yingmei, Guo, Lian-Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360452/
https://www.ncbi.nlm.nih.gov/pubmed/28356707