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Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance

The increasing use of polymyxins(1) in addition to the dissemination of plasmid-borne colistin resistance threatens to cause a serious breach in our last line of defense against multidrug resistant Gram-negative pathogens, and heralds the emergence of truly pan-resistant infections. Colistin resista...

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Detalles Bibliográficos
Autores principales: Stokes, Jonathan M., MacNair, Craig R., Ilyas, Bushra, French, Shawn, Côté, Jean-Philippe, Bouwman, Catrien, Farha, Maya A., Sieron, Arthur O., Whitfield, Chris, Coombes, Brian K., Brown, Eric D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360458/
https://www.ncbi.nlm.nih.gov/pubmed/28263303
http://dx.doi.org/10.1038/nmicrobiol.2017.28