Early transcriptional and epigenetic regulation of CD8(+) T cell differentiation revealed by single-cell RNA-seq

During microbial infection, responding CD8(+) T lymphocytes differentiate into heterogeneous subsets that together provide immediate and durable protection. To elucidate the dynamic transcriptional changes that underlie this process, we applied a single-cell RNA sequencing approach and analyzed indi...

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Detalles Bibliográficos
Autores principales: Kakaradov, Boyko, Arsenio, Janilyn, Widjaja, Christella E., He, Zhaoren, Aigner, Stefan, Metz, Patrick J., Yu, Bingfei, Wehrens, Ellen J., Lopez, Justine, Kim, Stephanie H., Zuniga, Elina I., Goldrath, Ananda W., Chang, John T., Yeo, Gene W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360497/
https://www.ncbi.nlm.nih.gov/pubmed/28218746
http://dx.doi.org/10.1038/ni.3688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360497/
https://www.ncbi.nlm.nih.gov/pubmed/28218746
http://dx.doi.org/10.1038/ni.3688

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