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Differential requirements for the canonical NF-κB transcription factors c-REL and RELA during the generation and activation of mature B-cells

Signaling through the canonical NF-κB pathway is critical for the generation and maintenance of mature B-cells and for antigen-dependent B-cell activation. c-REL (rel) and RELA (rela) are the downstream transcriptional activators of the canonical NF-κB pathway. Studies of B-cells derived from consti...

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Detalles Bibliográficos
Autores principales: Milanovic, Maja, Heise, Nicole, De Silva, Nilushi S., Anderson, Michael M., Silva, Kathryn, Carette, Amanda, Orelli, Fabiano, Bhagat, Govind, Klein, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360551/
https://www.ncbi.nlm.nih.gov/pubmed/27649781
http://dx.doi.org/10.1038/icb.2016.95