A cDNA Clone-Launched Platform for High-Yield Production of Inactivated Zika Vaccine

A purified inactivated vaccine (PIV) using the Zika virus (ZIKV) Puerto Rico strain PRVABC59 showed efficacy in monkeys, and is currently in a phase I clinical trial. High-yield manufacture of this PIV is essential for its development and vaccine access. Here we report an infectious cDNA clone-launc...

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Detalles Bibliográficos
Autores principales: Yang, Yujiao, Shan, Chao, Zou, Jing, Muruato, Antonio E., Bruno, Diniz Nunes, de Almeida Medeiros Daniele, Barbosa, Vasconcelos, Pedro F.C., Rossi, Shannan L., Weaver, Scott C., Xie, Xuping, Shi, Pei-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360567/
https://www.ncbi.nlm.nih.gov/pubmed/28196656
http://dx.doi.org/10.1016/j.ebiom.2017.02.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360567/
https://www.ncbi.nlm.nih.gov/pubmed/28196656
http://dx.doi.org/10.1016/j.ebiom.2017.02.003

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