African Genetic Diversity: Implications for Cytochrome P450-mediated Drug Metabolism and Drug Development

Genetic diversity is greater in Africa than in other continental populations. Genetic variability in genes encoding drug metabolizing enzymes may contribute to the high numbers of adverse drug reactions reported in Africa. We reviewed publications (1995–April 2016) reporting frequencies of known cyt...

Descripción completa

Detalles Bibliográficos
Autores principales: Rajman, Iris, Knapp, Laura, Morgan, Thomas, Masimirembwa, Collen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360579/
https://www.ncbi.nlm.nih.gov/pubmed/28237373
http://dx.doi.org/10.1016/j.ebiom.2017.02.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360579/
https://www.ncbi.nlm.nih.gov/pubmed/28237373
http://dx.doi.org/10.1016/j.ebiom.2017.02.017

Ejemplares similares