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African Genetic Diversity: Implications for Cytochrome P450-mediated Drug Metabolism and Drug Development
Genetic diversity is greater in Africa than in other continental populations. Genetic variability in genes encoding drug metabolizing enzymes may contribute to the high numbers of adverse drug reactions reported in Africa. We reviewed publications (1995–April 2016) reporting frequencies of known cyt...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360579/ https://www.ncbi.nlm.nih.gov/pubmed/28237373 http://dx.doi.org/10.1016/j.ebiom.2017.02.017 |