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Efficacy and Blood Plasmalogen Changes by Oral Administration of Plasmalogen in Patients with Mild Alzheimer's Disease and Mild Cognitive Impairment: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial

BACKGROUND: Plasmalogens (Pls) reportedly decreased in postmortem brain and in the blood of patients with Alzheimer's disease (AD). Recently we showed that intraperitoneal administration of Pls improved cognitive function in experimental animals. In the present trial, we tested the efficacy of...

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Detalles Bibliográficos
Autores principales: Fujino, Takehiko, Yamada, Tatsuo, Asada, Takashi, Tsuboi, Yoshio, Wakana, Chikako, Mawatari, Shiro, Kono, Suminori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360580/
https://www.ncbi.nlm.nih.gov/pubmed/28259590
http://dx.doi.org/10.1016/j.ebiom.2017.02.012