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Efficacy and Blood Plasmalogen Changes by Oral Administration of Plasmalogen in Patients with Mild Alzheimer's Disease and Mild Cognitive Impairment: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial
BACKGROUND: Plasmalogens (Pls) reportedly decreased in postmortem brain and in the blood of patients with Alzheimer's disease (AD). Recently we showed that intraperitoneal administration of Pls improved cognitive function in experimental animals. In the present trial, we tested the efficacy of...
Autores principales: | Fujino, Takehiko, Yamada, Tatsuo, Asada, Takashi, Tsuboi, Yoshio, Wakana, Chikako, Mawatari, Shiro, Kono, Suminori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360580/ https://www.ncbi.nlm.nih.gov/pubmed/28259590 http://dx.doi.org/10.1016/j.ebiom.2017.02.012 |
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