The Ubiquitination, Disaggregation and Proteasomal Degradation Machineries in Polyglutamine Disease

Polyglutamine disorders are chronic, progressive neurodegenerative diseases caused by expansion of a glutamine tract in widely expressed genes. Despite excellent models of disease, a well-documented clinical history and progression, and established genetic causes, there are no FDA approved, disease...

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Detalles Bibliográficos
Autores principales: Nath, Samir R., Lieberman, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360718/
https://www.ncbi.nlm.nih.gov/pubmed/28381987
http://dx.doi.org/10.3389/fnmol.2017.00078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360718/
https://www.ncbi.nlm.nih.gov/pubmed/28381987
http://dx.doi.org/10.3389/fnmol.2017.00078

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