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Knockdown of Long Non-Coding RNA KCNQ1OT1 Restrained Glioma Cells’ Malignancy by Activating miR-370/CCNE2 Axis

Accumulating evidence has highlighted the potential role of long non-coding RNAs (lncRNAs) as biomarkers and therapeutic targets in solid tumors. Here, we elucidated the function and possible molecular mechanisms of lncRNA KCNQ1OT1 in human glioma U87 and U251 cells. Quantitative Real-Time polymeras...

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Detalles Bibliográficos
Autores principales: Gong, Wei, Zheng, Jian, Liu, Xiaobai, Liu, Yunhui, Guo, Junqing, Gao, Yana, Tao, Wei, Chen, Jiajia, Li, Zhiqing, Ma, Jun, Xue, Yixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360732/
https://www.ncbi.nlm.nih.gov/pubmed/28381990
http://dx.doi.org/10.3389/fncel.2017.00084