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Bioavailability of generic 0.05% difluprednate emulsion in the aqueous humor, cornea, and conjunctiva of New Zealand rabbits after a single dose compared with commercial difluprednate

BACKGROUND: To determine the concentration after a single dose of generic 0.05% difluprednate and commercial difluprednate in the aqueous humor, cornea, and conjunctiva of New Zealand rabbits, a preclinical study in 72 male New Zealand white rabbits was performed. A single dose (50 μL) of two 0.05%...

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Detalles Bibliográficos
Autores principales: Mercado-Sesma, Arieh, Contreras-Rubio, Angélica, Baiza-Durán, Leopoldo, Olvera-Montaño, Oscar, Miranda-Robles, Mónica, Bonilla-García, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360744/
https://www.ncbi.nlm.nih.gov/pubmed/28324274
http://dx.doi.org/10.1186/s12348-017-0127-2