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Adult Lysophosphatidic Acid Receptor 1-Deficient Rats with Hyperoxia-Induced Neonatal Chronic Lung Disease Are Protected against Lipopolysaccharide-Induced Acute Lung Injury

Aim: Survivors of neonatal chronic lung disease or bronchopulmonary dysplasia (BPD) suffer from compromised lung function and are at high risk for developing lung injury by multiple insults later in life. Because neonatal lysophosphatidic acid receptor-1 (LPAR1)-deficient rats are protected against...

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Detalles Bibliográficos
Autores principales: Chen, Xueyu, Walther, Frans J., Laghmani, El H., Hoogeboom, Annemarie M., Hogen-Esch, Anne C. B., van Ark, Ingrid, Folkerts, Gert, Wagenaar, Gerry T. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360762/
https://www.ncbi.nlm.nih.gov/pubmed/28382003
http://dx.doi.org/10.3389/fphys.2017.00155