Prevention of Streptozotocin-Induced Diabetic Nephropathy by MG132: Possible Roles of Nrf2 and IκB

Our previous study showed that proteasomal inhibitor MG132 can prevent diabetic nephropathy (DN) along with upregulation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2). The present study was to investigate whether MG132 can prevent DN in wild-type and Nrf2-KO mice. Type 1 diabetes was induced...

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Detalles Bibliográficos
Autores principales: Kong, Lili, Wang, Yangwei, Luo, Manyu, Tan, Yi, Cui, Wenpeng, Miao, Lining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360973/
https://www.ncbi.nlm.nih.gov/pubmed/28373900
http://dx.doi.org/10.1155/2017/3671751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360973/
https://www.ncbi.nlm.nih.gov/pubmed/28373900
http://dx.doi.org/10.1155/2017/3671751

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