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Reperfusion Therapy with Rapamycin Attenuates Myocardial Infarction through Activation of AKT and ERK

Prompt coronary reperfusion is the gold standard for minimizing injury following acute myocardial infarction. Rapamycin, mammalian target of Rapamycin (mTOR) inhibitor, exerts preconditioning-like cardioprotective effects against ischemia/reperfusion (I/R) injury. We hypothesized that Rapamycin, giv...

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Detalles Bibliográficos
Autores principales: Filippone, Scott M., Samidurai, Arun, Roh, Sean K., Cain, Chad K., He, Jun, Salloum, Fadi N., Kukreja, Rakesh C., Das, Anindita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360974/
https://www.ncbi.nlm.nih.gov/pubmed/28373901
http://dx.doi.org/10.1155/2017/4619720