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An easy method for preparation of Cre-loxP regulated fluorescent adenoviral expression vectors and its application for direct reprogramming into hepatocytes

The recombinant adenoviral gene expression system is a powerful tool for gene delivery. However, it is difficult to obtain high titers of infectious virus, principally due to the toxicity of the expressed gene which affects on virus replication in the host HEK293 cells. To avoid these problems, we g...

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Detalles Bibliográficos
Autores principales: Kurihara, Chitose, Nakade, Koji, Pan, Jianzhi, Huang, Jing, Wasylyk, Bohdan, Obata, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361070/
https://www.ncbi.nlm.nih.gov/pubmed/28352551
http://dx.doi.org/10.1016/j.btre.2016.10.003