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8-Styryl-substituted coralyne derivatives as DNA binding fluorescent probes

Six new 8-styryl-substituted coralyne derivatives 4a–f were synthesized from coralyne (2) by a base catalysed Knoevenagel type reaction. It was shown by photometric and fluorimetric titrations of double stranded and quadruplex DNA to 4b–d as well as by fluorimetric DNA denaturation experiments that...

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Detalles Bibliográficos
Autores principales: Pithan, P. M., Decker, D., Druzhinin, S. I., Ihmels, H., Schönherr, H., Voß, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361113/
https://www.ncbi.nlm.nih.gov/pubmed/28496973
http://dx.doi.org/10.1039/c6ra27684a