Global DNA Methylation Analysis Identifies Two Discrete clusters of Pheochromocytoma with Distinct Genomic and Genetic Alterations

Pheochromocytomas and paragangliomas (PPGLs) are rare and frequently heritable neural-crest derived tumours arising from the adrenal medulla or extra-adrenal chromaffin cells respectively. The majority of PPGL tumours are benign and do not recur with distant metastases. However, a sizeable fraction...

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Detalles Bibliográficos
Autores principales: Backman, Samuel, Maharjan, Rajani, Falk-Delgado, Alberto, Crona, Joakim, Cupisti, Kenko, Stålberg, Peter, Hellman, Per, Björklund, Peyman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361146/
https://www.ncbi.nlm.nih.gov/pubmed/28327598
http://dx.doi.org/10.1038/srep44943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361146/
https://www.ncbi.nlm.nih.gov/pubmed/28327598
http://dx.doi.org/10.1038/srep44943

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