KDM4B histone demethylase and G9a regulate expression of vascular adhesion proteins in cerebral microvessels

Intercellular adhesion molecule 1 (ICAM1) mediates the adhesion and transmigration of leukocytes across the endothelium, promoting inflammation. We investigated the epigenetic mechanism regulating ICAM1 expression. The pro-inflammatory cytokine TNF-α dramatically increased ICAM1 mRNA and protein lev...

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Detalles Bibliográficos
Autores principales: Choi, Ji-Young, Yoon, Sang-Sun, Kim, Sang-Eun, Ahn Jo, Sangmee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361151/
https://www.ncbi.nlm.nih.gov/pubmed/28327608
http://dx.doi.org/10.1038/srep45005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361151/
https://www.ncbi.nlm.nih.gov/pubmed/28327608
http://dx.doi.org/10.1038/srep45005

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