Dynasore impairs VEGFR2 signalling in an endocytosis-independent manner

VEGFR2 is a critical angiogenic receptor playing a key role in vascular homeostasis. Upon activation by VEGF, VEGFR2 becomes endocytosed. Internalisation of VEGFR2 is facilitated, in part, through clathrin mediated endocytosis (CME), the role of which in VEGFR2 function is debated. Here, we confirm...

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Detalles Bibliográficos
Autores principales: Basagiannis, Dimitris, Zografou, Sofia, Galanopoulou, Katerina, Christoforidis, Savvas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361198/
https://www.ncbi.nlm.nih.gov/pubmed/28327657
http://dx.doi.org/10.1038/srep45035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361198/
https://www.ncbi.nlm.nih.gov/pubmed/28327657
http://dx.doi.org/10.1038/srep45035

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