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Scleraxis is required for maturation of tissue domains for proper integration of the musculoskeletal system

Scleraxis (Scx) is a basic helix-loop-helix transcription factor that is expressed persistently in tendons/ligaments, but transiently in entheseal cartilage. In this study, we generated a novel Scx(Cre) knock-in (KI) allele, by in-frame replacement of most of Scx exon 1 with Cre recombinase (Cre), t...

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Detalles Bibliográficos
Autores principales: Yoshimoto, Yuki, Takimoto, Aki, Watanabe, Hitomi, Hiraki, Yuji, Kondoh, Gen, Shukunami, Chisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361204/
https://www.ncbi.nlm.nih.gov/pubmed/28327634
http://dx.doi.org/10.1038/srep45010