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Scleraxis is required for maturation of tissue domains for proper integration of the musculoskeletal system
Scleraxis (Scx) is a basic helix-loop-helix transcription factor that is expressed persistently in tendons/ligaments, but transiently in entheseal cartilage. In this study, we generated a novel Scx(Cre) knock-in (KI) allele, by in-frame replacement of most of Scx exon 1 with Cre recombinase (Cre), t...
Autores principales: | Yoshimoto, Yuki, Takimoto, Aki, Watanabe, Hitomi, Hiraki, Yuji, Kondoh, Gen, Shukunami, Chisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361204/ https://www.ncbi.nlm.nih.gov/pubmed/28327634 http://dx.doi.org/10.1038/srep45010 |
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