Cargando…

Monitoring of dynamic changes in Keyhole Limpet Hemocyanin (KLH)-specific B cells in KLH-vaccinated cancer patients

Keyhole limpet hemocyanin (KLH) is used as an immunogenic neo-antigen for various clinical applications and during vaccine development. For advanced monitoring of KLH-based interventions, we developed a flow cytometry-based assay for the ex vivo detection, phenotyping and isolation of KLH-specific B...

Descripción completa

Detalles Bibliográficos
Autores principales: Wimmers, Florian, de Haas, Nienke, Scholzen, Anja, Schreibelt, Gerty, Simonetti, Elles, Eleveld, Marc J., Brouwers, Huberdina M. L. M., Beldhuis-Valkis, Marjo, Joosten, Irma, de Jonge, Marien I., Gerritsen, Winald R., de Vries, I. Jolanda M., Diavatopoulos, Dimitri A., Jacobs, Joannes F. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361210/
https://www.ncbi.nlm.nih.gov/pubmed/28344338
http://dx.doi.org/10.1038/srep43486