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Broad spectrum antiviral activity for paramyxoviruses is modulated by biophysical properties of fusion inhibitory peptides

Human paramyxoviruses include global causes of lower respiratory disease like the parainfluenza viruses, as well as agents of lethal encephalitis like Nipah virus. Infection is initiated by viral glycoprotein-mediated fusion between viral and host cell membranes. Paramyxovirus viral fusion proteins...

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Detalles Bibliográficos
Autores principales: Mathieu, Cyrille, Augusto, Marcelo T., Niewiesk, Stefan, Horvat, Branka, Palermo, Laura M., Sanna, Giuseppina, Madeddu, Silvia, Huey, Devra, Castanho, Miguel A. R. B., Porotto, Matteo, Santos, Nuno C., Moscona, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361215/
https://www.ncbi.nlm.nih.gov/pubmed/28344321
http://dx.doi.org/10.1038/srep43610