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Edaravone protects against oxygen-glucose-serum deprivation/restoration-induced apoptosis in spinal cord astrocytes by inhibiting integrated stress response

We previously found that oxygen-glucose-serum deprivation/restoration (OGSD/R) induces apoptosis of spinal cord astrocytes, possibly via caspase-12 and the integrated stress response, which involves protein kinase R-like endoplasmic reticulum kinase (PERK), eukaryotic initiation factor 2-alpha (eIF2...

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Detalles Bibliográficos
Autores principales: Dai, Bin, Yan, Ting, Shen, Yi-xing, Xu, You-jia, Shen, Hai-bin, Chen, Dong, Wang, Jin-rong, He, Shuang-hua, Dong, Qi-rong, Zhang, Ai-liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361514/
https://www.ncbi.nlm.nih.gov/pubmed/28400812
http://dx.doi.org/10.4103/1673-5374.199006