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Adenyl cyclase activator forskolin protects against Huntington's disease-like neurodegenerative disorders

Long term suppression of succinate dehydrogenase by selective inhibitor 3-nitropropionic acid has been used in rodents to model Huntington's disease where mitochondrial dysfunction and oxidative damages are primary pathological hallmarks for neuronal damage. Improvements in learning and memory...

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Detalles Bibliográficos
Autores principales: Mehan, Sidharth, Parveen, Shaba, Kalra, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361515/
https://www.ncbi.nlm.nih.gov/pubmed/28400813
http://dx.doi.org/10.4103/1673-5374.200812