Arap1 Deficiency Causes Photoreceptor Degeneration in Mice

PURPOSE: Small guanosine triphosphatase (GTPase) ADP-ribosylation factors (Arfs) regulate membrane traffic and actin reorganization under the control of GTPase-activating proteins (GAPs). Arap1 is an Arf-directed GAP that inhibits the trafficking of epidermal growth factor receptor (EGFR) to the ear...

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Detalles Bibliográficos
Autores principales: Moshiri, Ala, Humpal, Devin, Leonard, Brian C., Imai, Denise M., Tham, Addy, Bower, Lynette, Clary, Dave, Glaser, Thomas M., Lloyd, K. C. Kent, Murphy, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361582/
https://www.ncbi.nlm.nih.gov/pubmed/28324111
http://dx.doi.org/10.1167/iovs.16-20062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361582/
https://www.ncbi.nlm.nih.gov/pubmed/28324111
http://dx.doi.org/10.1167/iovs.16-20062

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