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Arap1 Deficiency Causes Photoreceptor Degeneration in Mice

PURPOSE: Small guanosine triphosphatase (GTPase) ADP-ribosylation factors (Arfs) regulate membrane traffic and actin reorganization under the control of GTPase-activating proteins (GAPs). Arap1 is an Arf-directed GAP that inhibits the trafficking of epidermal growth factor receptor (EGFR) to the ear...

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Detalles Bibliográficos
Autores principales:	Moshiri, Ala, Humpal, Devin, Leonard, Brian C., Imai, Denise M., Tham, Addy, Bower, Lynette, Clary, Dave, Glaser, Thomas M., Lloyd, K. C. Kent, Murphy, Christopher J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2017
Materias:	Retina
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361582/ https://www.ncbi.nlm.nih.gov/pubmed/28324111 http://dx.doi.org/10.1167/iovs.16-20062

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