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Targeting of chromatin readers: a novel strategy used by the Shigella flexneri virulence effector OspF to reprogram transcription

Shigella flexneri, a gram-negative bacterium responsible of bacillary dysentery, uses multiple strategies to overcome host immune defense. We have decrypted how this bacterium manipulates host-cell chromatin binders to take control of immune gene expression. We found that OspF, an injected virulence...

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Detalles Bibliográficos
Autores principales: Harouz, Habiba, Rachez, Christophe, Meijer, Benoit, Muchardt, Christian, Arbibe, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361648/
https://www.ncbi.nlm.nih.gov/pubmed/28357260
http://dx.doi.org/10.15698/mic2015.01.183