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Occlusion of the Ribosome Binding Site Connects the Translational Initiation Frequency, mRNA Stability and Premature Transcription Termination

Protein production is controlled by ribosome binding to the messenger RNA (mRNA), quantified in part by the binding affinity between the ribosome and the ribosome binding sequence on the mRNA. Using the E. coli lac operon as model, Ringquist et al. (1992) found a more than 1,000-fold difference in p...

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Detalles Bibliográficos
Autores principales: Eriksen, Mette, Sneppen, Kim, Pedersen, Steen, Mitarai, Namiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361652/
https://www.ncbi.nlm.nih.gov/pubmed/28382022
http://dx.doi.org/10.3389/fmicb.2017.00362