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Occlusion of the Ribosome Binding Site Connects the Translational Initiation Frequency, mRNA Stability and Premature Transcription Termination
Protein production is controlled by ribosome binding to the messenger RNA (mRNA), quantified in part by the binding affinity between the ribosome and the ribosome binding sequence on the mRNA. Using the E. coli lac operon as model, Ringquist et al. (1992) found a more than 1,000-fold difference in p...
Autores principales: | Eriksen, Mette, Sneppen, Kim, Pedersen, Steen, Mitarai, Namiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361652/ https://www.ncbi.nlm.nih.gov/pubmed/28382022 http://dx.doi.org/10.3389/fmicb.2017.00362 |
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