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Changes in macroautophagy, chaperone-mediated autophagy, and mitochondrial metabolism in murine skeletal and cardiac muscle during aging

Aging causes a general decline in cellular metabolic activity, and function in different tissues and whole body homeostasis. However, the understanding about the metabolomic and autophagy changes in skeletal muscle and heart during aging is still limited. We thus examined markers for macroautophagy,...

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Detalles Bibliográficos
Autores principales: Zhou, Jin, Yun Chong, Shu, Lim, Andrea, Singh, Brijesh K., Sinha, Rohit A., Salmon, Adam B., Yen, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361683/
https://www.ncbi.nlm.nih.gov/pubmed/28238968
http://dx.doi.org/10.18632/aging.101181