DNA double-strand breaks in human induced pluripotent stem cell reprogramming and long-term in vitro culturing

BACKGROUND: Human induced pluripotent stem cells (hiPSCs) play roles in both disease modelling and regenerative medicine. It is critical that the genomic integrity of the cells remains intact and that the DNA repair systems are fully functional. In this article, we focused on the detection of DNA do...

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Detalles Bibliográficos
Autores principales: Simara, Pavel, Tesarova, Lenka, Rehakova, Daniela, Matula, Pavel, Stejskal, Stanislav, Hampl, Ales, Koutna, Irena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361733/
https://www.ncbi.nlm.nih.gov/pubmed/28327192
http://dx.doi.org/10.1186/s13287-017-0522-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361733/
https://www.ncbi.nlm.nih.gov/pubmed/28327192
http://dx.doi.org/10.1186/s13287-017-0522-5

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